Selected journal papers2014Adamson RH, Clark JF, Radeva MY, Jiang Y, Kheirolomoom A, Ferrara KW, Curry FR. Albumin modulates A1P delivery from red blood cells in perfused microvessels: mechanism of the protein effect. Am J Physiol Heart Circ Physiol. 2014 Feb 14. [Epub ahead of print] Paoli EE, Ingham ES, Zhang H, Mahakian LM, Fite BZ, Gagnon MK, Tam S, Kheirolomoom A, Cardiff RD, Ferrara KW. Accumulation, internalization and therapeutic efficacy of neuropilin-1-targeted liposomes. J Control Release. 2014 Jan 13;178C:108-117. Seo JW, Baek H, Mahakian LM, Kusunose J, Hamzah J, Ruoslahti E, Ferrara KW. (64)Cu-Labeled LyP-1-Dendrimer for PET-CT Imaging of Atherosclerotic Plaque. Bioconjug Chem. 2014 Feb 19;25(2):231-9. Lanza GM, Moonen C, Baker JR, Chang E, Cheng Z, Grodzinski P, Ferrara KW, Hynynen K, Kelloff G, Lee YK, Patri A, Sept D, Schnitzer JE, Wood B, Zhang M, Zheng G, Farahani K. Assessing the barriers to image-guided drug delivery. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2014 Jan;6(1):1-14. Kusunose J, Gagnon MK, Seo JW, Ferrara KW. Quantitation of nanoparticle accumulation in flow using optimized microfluidic chambers. Journal of Drug Targeting. 2014 Jan;22(1):48-56. Lai CY, Kruse DE, Ferrara KW, Caskey CF. Creation and characterization of an ultrasound and CT phantom for non-invasive ultrasound thermometry calibration. IEEE Trans BME. 2014 Feb; 61(2):502-512. Qin S, Fite BZ; Gagnon K, Curry FR, Thorsen F, Ferrara KW. A physiological perspective on the use of imaging to assess the in vivo delivery of therapeutics. Annals of Biomedical Engineering, Ann Biomed Eng. 2014 Feb;42(2):280-98. Mahakian LM, Farwell DG, Zhang H, Seo JW, Poirier B, Tinling SP, Afify A, Haynam EM, Shaye D, Ferrara KW. Comparison of PET imaging with 64Cu-liposomes and 18F-FDG in the 7,12–dimethylbenz[a]anthracene (DMBA) induced hamster buccal pouch model of oral dysplasia and squamous cell carcinoma. Molecular Imaging and Biology, 2013 Sep 10. [Epub ahead of print]. 2013Son DJ, Kumar S, Takabe W, Kim CW, Ni CW, Alberts-Grill N, Jang I, Kim SO, Kim WK, Kang SW, Baker AH, Seo JW, Ferrara KW, Jo H. The atypical mechanosensitive microRNA-712 derived from pre-ribosomal RNA induces endothelial inflammation and atherosclerosis, Nature Communications, 2013 Dec 18;4:3000. Thorsen F, Fite B, Mahakian LM, Seo JW, Qin S, Harrison V, Johnson S, Ingham ES, Meade TJ, Caskey CF, Sundstrøm T, Harter P, Skaftnesmo KO, Ferrara KW. Multimodal imaging enables early detection and characterization of changes in tumor permeability of brain metastases. J Control Release. 2013 Dec 28;172(3):812-22. Dube N, Shu JY, Dong H, Seo JW, Ingham E, Kheirolomoom A, Chen PY, Forsayeth J, Bankiewicz K, Ferrara KW, Xu T. Evaluation of Doxorubicin-loaded 3-Helix Micelles as Nanocarriers. Biomacromolecules. 2013 Oct 14;14(10):3697-705. Kheirolomoom A, Lai CY, Ingham ES, Tam SM, Mahakian LM, Watson KD, Ferrara KW. Complete regression of local cancer with minimal toxicity by multiple administrations of doxorubicin stabilized in temperature-sensitive liposomes combined with ultrasound-mediated hyperthermia. Journal of Controlled Release, 2013 Nov 28;172(1):266-73. Lai CY, Fite BZ, Ferrara, KW et al. Ultrasonic enhancement of drug penetration in solid tumors. Frontiers in Oncology, 2013;3:204. doi: 10.3389/fonc.2013.00204. PMCID: PMC3746679. Lai CY, Kruse DE, Seo JW, Kheirolomoom A, Ferrara KW. A phantom for visualization of three-dimensional drug release by ultrasound-induced mild hyperthermia. Med Phys. 2013 Aug;40(8):083301. doi: 10.1118/1.4813299, PMC3739833. Hu X, Caskey CF, Mahakian LM, Kruse DE, Beegle JR, Declèves AE, Rychak JJ, Sutcliffe PL, Sharma K, Ferrara KW. In vivo validation and 3D visualization of broadband ultrasound molecular imaging. AJNMMI, 2013 Jul 10;3(4):336-49, 2013 Jul 10;3(4):336-49, PMC3715778. Zhang G, Panigrahy D, Mahakian LM, Yang J, Liu JY, Stephen Lee KS, Wettersten HI, Ulu A, Hu X, Tam S, Hwang SH, Ingham ES, Kieran MW, Weiss RH, Ferrara KW, Hammock BD. Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth and metastasis. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6530-5. doi: 10.1073/pnas.1304321110. Epub 2013 Apr 3, PMC3631682. Malik ZA, Kott KS, Poe AJ, Kuo T, Chen L, Ferrara KW, Knowlton AA. Cardiac myocyte exosomes: stability, HSP60, and proteomics. Am J Physiol Heart Circ Physiol. 2013 Apr; 304(7):H954-65. Epub 2013 Feb 1, PMC3625894. Wong AW, Ormsby E, Zhang H, Seo JW, Mahakian LM, Caskey CF, Ferrara KW. A comparison of image contrast with (64)Cu-labeled long circulating liposomes and (18)F-FDG in a murine model of mammary carcinoma. Am J Nucl Med Mol Imaging. 2013;3(1):32-43. Epub 2013 Jan 5, PMC3545363. Kusunose J, Zhang H, Gagnon MK, Pan T, Simon SI, Ferrara KW. Microfluidic system for facilitated quantification of nanoparticle accumulation to cells under laminar flow. Ann Biomed Eng. 2013 Jan;41(1):89-99. Epub 2012 Aug 2, PMC3505813. 2012Zhang H, Li N, Sirish P, Mahakian L, Ingham E, Curry FR, Yamada S, Chiamvimonvat N, Ferrara KW, The cargo of CRPPR-conjugated liposomes crosses the intact murine cardiac endothelium, Journal of Controlled Release, in press. Perng JK, Lee S, Kundu K, Caskey CF, Knight SF, Satir S, Ferrara KW, Taylor WR, Degertekin FL, Sorescu D, Murthy N, Ultrasound imaging of reactive oxygen species (ROS) by chemically-generated microbubbles, Ann Biomed Eng. 2012 May 5. [Epub ahead of print]. Dong H, Dube N, Shu JY, Seo JW, Mahakian LM, Ferrara KW, Xu T. Long-Circulating 15 nm Micelles Based on Amphiphilic 3-Helix Peptide-PEG Conjugates. ACS Nano. 2012 Jun 26;6(6):5320-9. Epub 2012 May 4. Fite BZ, Liu Y, Kruse DE, Caskey CF, Walton JH, Lai CY, Mahakian LM, Larrat B, Dumont E, Ferrara KW, Magnetic Resonance Thermometry at 7T for Real-Time Monitoring and Correction of Ultrasound Induced Mild Hyperthermia, PLoS ONE 7(4): e35509. doi:10.1371/journal.pone.0035509. Hu, X, Kheirolomoom, A, Mahakian, LM, Beegle, JR, Kruse, DE, Lam, KS, Ferrara, KW, Insonation of Targeted Microbubbles Produces Regions of Reduced Blood Flow within Tumor Vasculature, Invest Radiol. 2012 Jul;47(7):398-405. Watson KD, Lai CY, Qin S, Kruse DE, Lin YC, Seo JW, Cardiff RD, Mahakian LM, Beegle J, Ingham ES, Curry FR, Reed RK, Ferrara KW. Ultrasound increases nanoparticle delivery by reducing intratumoral pressure and increasing transport in epithelial and epithelial-mesenchymal transition tumors. Cancer Research. 2012 Mar 15;72(6):1485-93. Epub 2012 Jan 26. 2011Charles F. Caskey, Mario Hlawitschka, Shengping Qin, Lisa M. Mahakian, Robert D. Cardiff, John M. Boone, Katherine W. Ferrara, An open environment CT-US fusion for tissue segmentation during interventional guidance, PLoS One, 2011;6(11):e27372. Epub 2011 Nov 23. Mario Hlawitschka, Robert J. McGough, Katherine W. Ferrara, Dustin E. Kruse, Fast Ultrasound Beam Prediction for Linear and Regular Two-dimensional Arrays, IEEE Trans Ultrason Ferroelectr Freq Control. 2011 Aug;58(9), 2001-12. Caskey CF, Hu X, Ferrara KW. Leveraging the power of ultrasound for therapeutic design and optimization. J Control Release. 2011 Dec 20;156(3):297-306. Epub 2011 Jul 30. Stephens D, Kruse D, Qin S, Ferrara K. Design aspects of focal beams from high-intensity arrays. IEEE Trans Ultrason Ferroelectr Freq Control. 2011 Aug;58(8):1590-602. Hamzah J, Kotamraju VR, Seo JW, Agemy L, Fogal V, Mahakian LM, Peters D, Roth L, Gagnon MK, Ferrara KW, Ruoslahti E., Specific penetration and accumulation of a homing peptide within atherosclerotic plaques of apolipoprotein E-deficient mice. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):7154-9. Epub 2011 Apr 11. Watson KD, Hu X, Lai CY, Lindfors HA, Hu-Lowe DD, Tuthill TA, Shalinsky DR, Ferrara KW. Novel Ultrasound and DCE-MRI Analyses after Antiangiogenic Treatment with a Selective VEGF Receptor Inhibitor. Ultrasound Med Biol. 2011 Jun;37(6):909-21. Epub 2011 Apr 30. Kruse, DE, Stephens, DN, Lindfors, HA, Ingham, ES, Paoli, EE, and Ferrara, KW. A radio-frequency coupling network for heating of citrate-coated gold nanoparticles for cancer therapy: design and analysis. IEEE Trans Biomed Eng. 2011 Jul;58(7):2002-12. Epub 2011 Mar 10. Andreozzi E, Seo JW, Ferrara K, Louie A. A Novel Method to Label Solid Lipid Nanoparticles (SLNs) with Cu-64 for Positron Emission Tomography (PET) Imaging. Bioconjug Chem. 2011 Apr 20;22(4):808-18. Epub 2011 Mar 9. Seo JW, Qin S, Mahakian LM, Watson KD, Kheirolomoom A, Ferrara KW. Positron emission tomography imaging of the stability of Cu-64 labeled dipalmitoyl and distearoyl lipids in liposomes. J Control Release. 2011 Apr 10;151(1):28-34. Epub 2011 Jan 15. Anderson CR, Hu X, Zhang H, Tlaxca J, Declèves AE, Houghtaling R, Sharma K, Lawrence M, Ferrara KW, Rychak JJ. Ultrasound Molecular Imaging of Tumor Angiogenesis with an Integrin Targeted Microbubble Contrast Agent. Invest Radiol. 2011 Apr;46(4):215-24. Hu-Lowe DD, Chen E, Zhang L, Watson KD, Mancuso P, Lappin P, Wickman G, Chen JH, Wang J, Jiang X, Amundson K, Simon R, Erbersdobler A, Bergqvist S, Feng Z, Swanson TA, Simmons BH, Lippincott J, Casperson GF, Levin WJ, Gallo Stampino C, Shalinsky DR, Ferrara KW, Fiedler W, Bertolini F. Targeting Activin Receptor-Like Kinase 1 (ALK1) Inhibits Angiogenesis and Tumorigenesis Through a Mechanism of Action Complementary to Anti-VEGF Therapies. Cancer Res. 2011 Jan 6. PMID: 21212415 2010Lai CY, Kruse DE, Caskey CF, Stephens DN, Sutcliffe P, Ferrara KW. Noninvasive Thermometry Assisted by a Dual-Function Ultrasound Transducer for Mild Hyperthermia. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 57, no. 12, December 2010 Kheirolomoom A, Mahakian LM, Lai CY, Lindfors HA, Seo JW, Paoli EE, Watson KD, Haynam EM, Ingham ES, Xing L, Cheng RH, Borowsky AD, Cardiff RD, Ferrara KW. Copper-Doxorubicin as a nanoparticle cargo retains efficacy with minimal toxicity. Mol Pharm. 2010 Dec 6;7(6):1948-58.PMID: 20925429 Rygh CB, Qin S, Seo JW, Mahakian LM, Zhang H, Adamson RH, Chen JQ, Borowsky AD, Cardiff RD, Reed RK, Curry FR, Ferrara KW. Longitudinal investigation of permeability and distribution of macromolecules in mouse malignant transformation using PET. Clin Cancer Res. 2010 Nov 24. PMID: 21106723 Qin S, Ferrara KW. A model for the dynamics of ultrasound contrast agents in vivo. J Acoust Soc Am. 2010 Sep;128(3):1511-21. Seo JW, Mahakian LM, Kheirolomoom A, Zhang H, Meares CF, Ferdani R, Anderson CJ, Ferrara KW. Liposomal Cu-64 Labeling Method Using Bifunctional Chelators: Poly(ethylene glycol) Spacer and Chelator Effects. Bioconjug Chem. 2010 Jun 22. PMID: 20568726 Paoli EE, Kruse DE, Seo JW, Zhang H, Kheirolomoom A, Watson KD, Chiu P, Stahlberg H, Ferrara KW. An optical and microPET assessment of thermally-sensitive liposome biodistribution in the Met-1 tumor model: Importance of formulation. J Control Release. 2010 Apr 2;143(1):13-22. PMID: 20006659 Qin S, Seo JW, Zhang H, Qi J, Curry FR, Ferrara KW. An imaging-driven model for liposomal stability and circulation. Mol Pharm. 2010 Feb 1;7(1):12-21.PMID: 19621944 Kheirolomoom A, Kruse DE, Qin S, Watson KE, Lai CY, Young LJ, Cardiff RD, Ferrara KW. Enhanced in vivo bioluminescence imaging using liposomal luciferin delivery system. J Control Release. 2010 Jan 25;141(2):128-36. Epub 2009 Sep 11.PMID: 19748536 Kruse DE, Lai CY, Stephens DN, Sutcliffe P, Paoli EE, Barnes SH, Ferrara KW. Spatial and temporal-controlled tissue heating on a modified clinical ultrasound scanner for generating mild hyperthermia in tumors. IEEE Trans Biomed Eng. 2010 Jan;57(1):155-66.PMID: 20064754 Hu X, Zheng H, Kruse DE, Sutcliffe P, Stephens DN, Ferrara KW. A sensitive TLRH targeted imaging technique for ultrasonic molecular imaging. IEEE Trans Ultrason Ferroelectr Freq Control. 2010;57(2):305-16.PMID: 20178897 2009Pollard RE, Dayton PA, Watson KD, Hu X, Guracar IM, Ferrara KW. Motion corrected cadence CPS ultrasound for quantifying response to vasoactive drugs in a rat kidney model. Urology. 2009 Sep;74(3):675-81. PMID: 19589583 Ferrara KW, Borden MA, Zhang H. Lipid-shelled vehicles: engineering for ultrasound molecular imaging and drug delivery. Acc Chem Res. 2009 Jul 21;42(7):881-92.PMID: 19552457 Caskey CF, Qin S, Dayton PA, Ferrara KW. Microbubble tunneling in gel phantoms. J Acoust Soc Am. 2009 May;125(5):EL183-9. PMID: 19425620 Leu A, Stieger SM, Dayton P, Ferrara KW, Leach JK. Angiogenic response to bioactive glass promotes bone healing in an irradiated calvarial defect. Tissue Eng Part A. 2009 Apr;15(4):877-85. PMID: 18795867 Qin S, Caskey CF, Ferrara KW. Ultrasound contrast microbubbles in imaging and therapy: physical principles and engineering. Phys Med Biol. 2009 Mar 21;54(6):R27-57. PMID: 19229096 2008Seo JW, Zhang H, Kukis DL, Meares CF, Ferrara KW. A novel method to label preformed liposomes with 64Cu for positron emission tomography (PET) imaging. Bioconjug Chem. 2008 Dec;19(12):2577-84. PMID: 18991368 Tartis MS, Kruse DE, Zheng H, Zhang H, Kheirolomoom A, Marik J, Ferrara KW. Dynamic microPET imaging of ultrasound contrast agents and lipid delivery. J Control Release. 2008 Nov 12;131(3):160-6. PMID: 18718854 Stephens DN, Kruse DE, Ergun AS, Barnes S, Lu XM, Ferrara KW. Efficient array design for sonotherapy. Phys Med Biol. 2008 Jul 21;53(14):3943-69. PMID: 18591737 Kruse DE, Mackanos MA, O’Connell-Rodwell CE, Contag CH, Ferrara KW. Short-duration-focused ultrasound stimulation of Hsp70 expression in vivo. Phys Med Biol. 2008 Jul 7;53(13):3641-60. PMID: 18562783 Ferrara KW. Driving delivery vehicles with ultrasound. Adv Drug Deliv Rev. 2008 Jun 30;60(10):1097-102. PMID: 18479775 Qin S, Kruse DE, Ferrara KW. Transmitted ultrasound pressure variation in micro blood vessel phantoms. Ultrasound Med Biol. 2008 Jun;34(6):1014-20. PMID: 18395962 Zhang H, Kusunose J, Kheirolomoom A, Seo JW, Qi J, Watson KD, Lindfors HA, Ruoslahti E, Sutcliffe JL, Ferrara KW. Dynamic imaging of arginine-rich heart-targeted vehicles in a mouse model. Biomaterials. 2008 Apr;29(12):1976-88. PMID: 18255141 Borden MA, Zhang H, Gillies RJ, Dayton PA, Ferrara KW. A stimulus-responsive contrast agent for ultrasound molecular imaging. Biomaterials. 2008 Feb;29(5):597-606. PMID: 17977595 Zheng H, Kruse DE, Stephens DN, Ferrara KW, Sutcliffe P, Gardner E. A sensitive ultrasonic imaging method for targeted contrast microbubble detection. Conf Proc IEEE Eng Med Biol Soc. 2008;2008:5290-3. PMID: 19163911 Stieger SM, Dayton PA, Borden MA, Caskey CF, Griffey SM, Wisner ER, Ferrara KW. Imaging of angiogenesis using Cadence contrast pulse sequencing and targeted contrast agents. Contrast Media Mol Imaging. 2008 Jan;3(1):9-18. PMID: 18335479 2007Mark A. Borden, Charles Caskey, Erica Little, Robert J. Gillies & Katherine W. Ferrara, “DNA and polylysine adsorption and multilayer construction onto cationic lipid-coated microbubbles”,. Langmuir, epub August 3, 2007. Charles Caskey, Susanne Stieger, Shengping Qin, Paul Dayton, Katherine W. Ferrara, “Direct observation of microbubble interaction with the endothelium,” Journal of the Acoustical Society of America, 122(2) August, 2007, 1191-1200. Katherine Ferrara, Rachel Pollard, Mark Borden, “Ultrasound Microbubble Contrast Agents: Fundamentals and Application to Gene and Drug Delivery”, Annual Review of Biomedical Engineering, Vol. 9: 415-447 (Volume publication date August 2007) Azadeh Kheirolomoom, Katherine W. Ferrara, “Cholesterol transport from liposomal delivery vehicles,”Biomaterials, Jun 5, 2007. Shengping Qin, Katherine W. Ferrara, “The natural frequency of nonlinear oscillation of ultrasound contrast agents in microvessels,” Ultrasound in Medicine and Biology, Epub ahead of print, May 1, 2007. Susanne M. Stieger, Charles F. Caskey, S. Qin, Roger H. Adamson, Fitz-Roy E. Curry, Erik R. Wisner, Katherine W. Ferrara, “Enhancement of vascular permeability with low frequency contrast ultrasound,” Radiology, 2007 April, 243(1), 112-121. Shukui Zhao, Dustin E. Kruse, Katherine W. Ferrara, and Paul A. Dayton, “Selective imaging of adherent targeted ultrasound contrast agents,” Physics in Medicine and Biology, 52 (2007), 2055-2072. Yang Sun, Dustin E. Kruse, Katherine W. Ferrara, “Contrast imaging with chirped excitation,” IEEE Transactions on UFFC, March 2007, 54(3), 520-529. Azadeh Kheirolomoom, Paul A. Dayton, Aaron F.H. Lum, Katherine W. Ferrara, “Acoustically-active microbubbles conjugated to liposomes: Characterization of a proposed drug delivery vehicle,” Journal of Controlled Release, 2006 Dec 23. Jan Marik, Michaelann J. Shortencarier, Julie L. Sutcliffe-Goulden, Katherine W. Ferrara, “Long-circulating liposomes radiolabeled with [18F]fluorodipalmitin ([18F]FDP),” Nuclear Medicine in Biology, 2007 Feb;34(2):165-171. Pollard RE, Broumas AR, Wisner ER, Vekich SV, Ferrara KW, “Quantitative contrast enhanced ultrasound and ct assessment of tumor response to antiangiogenic therapy in rats,” Ultrasound in Medicine & Biology 2007 Feb;33(2):235-245. 2006Michaelann Shortencarier Tartis, Jennifer McCallan, Aaron F.H. Lum, Rachel LaBell, Susanne M. Stieger, Terry O. Matsunaga and Katherine W. Ferrara, “Therapeutic effects of paclitaxel-containing ultrasound contrast agents,” Ultrasound in Medicine & Biology, Volume 32, Issue 11, November 2006, Pages 1771-1780. Shukui Zhao, Dustin E. Kruse, Katherine W. Ferrara, and Paul A. Dayton, “Acoustic response from adherent targeted contrast agents”, Jasa Electronic Letters, 120(6), Dec. 2006, Epublished Oct. 2006, pp. EL63-EL69 Shengping Qin and Katherine W Ferrara, “Acoustic response of compliable microvessels containing ultrasound contrast agents”, Phys. Med. Biol. 51 (2006) 5065-5088, September, 2006 Paul Dayton, Shukui Zhao, Susannah Bloch, Patricia A Schumann, Kim Penrose, Terry O Matsunaga, Reena Zutshi, Alexander Doinikov and Katherine W Ferrara, “Application of ultrasound to selectively localize nanodroplets for targeted imaging and therapy”, Molecular Imaging, 5(3), July 2006 Mark A Borden, Melissa R Sarantos, Susanne M Stieger, Scott I Simon, Katherine W Ferrara and Paul Dayton, “Ultrasound Radiation Force Modulates Ligand Availability on Targeted Contrast Agents”, Molecular Imaging, 5(3), July 2006 R. Pollard, R. Yunis, D. Kueltz, P. Martin, S. Griffey, K. Ferrara, “Ultrasonic detection and characterization of polycystic kidney disease in a mouse model,” Comparative Medicine, 2006 Jun; 56(3):215-21 Yang Sun, Shukui Zhao, Paul A. Dayton and Katherine W. Ferrara, “Observation of contrast agent response to chirp insonation with a simultaneous optical-acoustical system,” IEEE Transactions on UFFC, June 2006, 53(6), 1130-1137 Stieger SM, Bloch SH, Foreman O, Wisner ER, Ferrara KW, Dayton P, “Ultrasound assessment of angiogenesis in a Matrigel model in rats,” Ultrasound in Medicine and Biology, May 2006, 32(5):673-81 A. Louie, J. Izatt, Katherine Ferrara, “Biomedical Imaging Graduate Curricula and Courses: Report from the 2005 Whitaker Biomedical Engineering Educational Summit,” Annals of Biomedical Engineering, Ann Biomed Eng. 2006 Feb;34(2):239-47. Epub 2006 Feb 16. Mark A. Borden, Josette Ricker, Nelly Tsvetkova, Marjorie Longo, Paul A.Dayton & Katherine W. Ferrara, “Lateral phase separation in lipid-monolayer coated microbubbles, Langmuir, 2006 Apr 25;22(9):4291-4297. Charles F. Caskey, Dustin E. Kruse, Paul A. Dayton, Tyler K. Kitano, Katherine W. Ferrara. “Microbubble Oscillation in Tubes with Diameters of 12, 25, and 195 Microns,” Applied Physics Letters 88, 033902, Epub ahead of print, 2006. 2005Aaron F H Lum, Mark A Borden, Paul A Dayton, Dustin E Kruse, Scott I Simon, Katherine W Ferrara, “Ultrasound Radiation Force Enables Targeted Deposition of Model Drug Carriers Loaded on Microbubbles,” Journal of Controlled Release, Epub ahead of print, 2005. Shukui Zhao, Katherine W. Ferrara, and Paul A. Dayton, ” Asymmetric oscillation of adherent targeted ultrasound contrast agents,” Applied Physics Letters 87, 134103-1-3, (2005). Mark A. Borden; Paul A. Dayton; Katherine W. Ferrara; ” Influence of Lipid Shell Physiochemical Properties on Ultrasound-Induced Microbubble Destruction,” IEEE Transactions on UFFC 25(11), November 2005, 1992-2002. Y. Sun, D. Kruse, P. Dayton, K. Ferrara, ” High-Frequency Dynamics of Ultrasound Contrast Agents ,” IEEE Transactions on UFFC 25(11), November 2005, 1981-91. Dustin Kruse, K. Ferrara, “ A New Imaging Strategy Utilizing Wideband Transient Response of Ultrasound Contrast Agents ,” IEEE Transactions on UFFC 52(8), August 2005, 1320-9. S. H. Bloch, R. E. Short, K. W. Ferrara, E. R. Wisner, ” The effect of size on the acoustic response of polymer shelled contrast agents ,” Ultrasound in Medicine and Biology 31(3): 439-44, 2005. Amy R. Broumas, Rachel E. Pollard, Susannah H. Bloch, Erik R. Wisner, Steven Griffey, and Katherine W. Ferrara, ” Contrast-enhanced computed tomography and ultrasound for the evaluation of tumor blood flow ,” Investigative Radiology 40(3): 134-147, 2005. Y.T. Hu, Shengping Qin, Ting Hu, Katherine W. Ferrara, Qing Jiang, “ Asymmetric oscillation of cavitation bubbles in a microvessal and its implications upon mechanisms of clinical vessel injury in shock-wave lithotripsy .” International Journal of Non-Linear Mechanics 40(2-3): 341-350, 2005. 2004S. H. Bloch, P. A. Dayton, and K. W. Ferrara, “Targeted imaging using ultrasound contrast agents ,” IEEE Engineering in Medicine and Biology Magazine 23(5): 18-29, 2004. S. H. Bloch, M. Wan, P. A. Dayton, and K. W. Ferrara, ” Optical observation of lipid- and polymer-shelled ultrasound microbubble contrast agents ,” Applied Physics Letters 84(4):631-3, 2004. P. A. Dayton, D. P. Pearson, J. Clark, S. I. Simon, P. Schumann, R. Zutshi, T. O. Matsunaga, and K. W. Ferrara, “Ultrasonic analysis of peptide- and antibody-targeted microbubble contrast agents for molecular imaging of alpha-v beta-3 expressing cells,” Molecular Imaging 3(2): 125-134, 2004. D. N. Patel, S. H. Bloch, P. A. Dayton, and K. W. Ferrara, ” Acoustic signatures of submicron contrast agents ,” IEEE Transactions on Ultrasonics Ferroelectrics & Frequency Control 51(3):293-301, 2004. R. E. Pollard, T. C. Garcia, S. M. Stieger, K. W. Ferrara, A. R. Sadlowski, and E. R. Wisner, ” Quantitative evaluation of peripheral tumor perfusion and permeability using contrast enhanced computed tomography ,” Investigative Radiology 39(6):340-9, 2004. M. J. Shortencarier, P. A. Dayton, S. H. Bloch, P. A. Schumann, T. O. Matsunaga, and K. W. Ferrara, “A method for Radiation-Force Localized Drug Delivery Using Gas-Filled Lipospheres,” IEEE Transactions on Ultrasonics Ferroelectrics & Frequency Control 51(7): 822-31, 2004. Chih-Kuang Yeh, Katherine W. Ferrara, and Dustin E. Kruse, “High resolution functional vascular assessment with ultrasound ,” IEEE Transactions on Medical Imaging 23(10): 1263-75, 2004. S. Zhao, M. Borden, S. H. Bloch, D. Kruse, K. W. Ferrara, and P. A. Dayton, “Radiation force assisted targeting facilitates ultrasonic molecular imaging ,” Molecular Imaging 3(3):135-148, 2004. 2003J. S. Allen, D. E. Kruse, P. A. Dayton, and K. W. Ferrara, ” Effect of coupled oscillations on microbubble behavior ,” Journal of the Acoustical Society of America 114(3):1678-90, 2003. J. E. Chomas, R. E. Pollard, A. R. Sadlowski, S. M. Griffey, E. R. Wisner, and K. W. Ferrara, ” Contrast-enhanced US of microcirculation of superficially implanted tumors in rats ,” Radiology 229(2):439-46, 2003. E. R. Wisner, K. W. Ferrara, R. E. Short, T. B. Ottoboni, J. D. Gabe, and D. Patel, “ Sentinel node detection using contrast-enhanced power Doppler ultrasound lymphography ,” Investigative Radiology 38(6):358-365, 2003. 2002J. S. Allen, D. J. May, and K. W. Ferrara, ” Dynamics of therapeutic ultrasound contrast agents ,” Ultrasound in Medicine and Biology 28(6):805-16, 2002. J. Chomas, P. Dayton, D. May, and K. Ferrara, ” Nondestructive subharmonic imaging ,” IEEE Transactions on Ultrasonics Ferroelectrics & Frequency Control 49(7):883-92, 2002. P. A. Dayton, J. S. Allen, and K. W. Ferrara, ” The magnitude of radiation force on ultrasound contrast agents ,” Journal of the Acoustical Society of America 112(5 Pt 1):2183-92, 2002. P. A. Dayton and K. W. Ferrara, ” Targeted imaging using ultrasound ,” Journal of Magnetic Resonance Imaging 16(4):362-77, 2002. D. E. Kruse and K. W. Ferrara, ” A new high resolution color flow system using an eigendecomposition-based adaptive filter for clutter rejection ,” IEEE Transactions on Ultrasonics Ferroelectrics & Frequency Control 49(12):1739-54, 2002. D. J. May, J. S. Allen, and K. W. Ferrara, ” Dynamics and fragmentation of thick-shelled microbubbles ,” IEEE Transactions on Ultrasonics Ferroelectrics & Frequency Control 49(10):1400-10, 2002. D. Patel, P. Dayton, J. Gut, E. Wisner, and K. W. Ferrara, ” Optical and acoustical interrogation of submicron contrast agents ,” IEEE Transactions on Ultrasonics Ferroelectrics & Frequency Control 49(12):1641-51, 2002. R. E. Pollard, A. R. Sadlowski, S. H. Bloch, L. Murray, E. R. Wisner, S. Griffey, and K. W. Ferrara, ” Contrast-assisted destruction-replenishment ultrasound for the assessment of tumor microvasculature in a rat model ,” Technology in Cancer Research and Treatment 1(6):459-70, 2002. R. H. Silverman, R. Ursea, D. Kruse, K. W. Ferrara, M. J. Rondeau, and D. J. Coleman, ” Ultrasound measurement of the effect of temperature on microperfusion in the eye ,” Ultrasound in Medicine and Biology 28(11-12):1413-9, 2002. E. R. Wisner, K. Ferrara, J. D. Gabe, D. Patel, T. G. Nyland, R. E. Short, and T. B. Ottoboni, ” Contrast enhanced intermittent power Doppler ultrasound with sub-micron bubbles for sentinel node detection ,” Academic Radiology 9(Suppl 2):S389-91, 2002. 2001J. S. Allen, D. E. Kruse, and K. W. Ferrara, “ Shell waves and acoustic scattering from ultrasound contrast agents ,” IEEE Transactions on Ultrasonics Ferroelectrics & Frequency Control 48(2):409-18, 2001. J. E. Chomas, P. Dayton, J. Allen, K. Morgan, and K. W. Ferrara, “ Mechanisms of contrast agent destruction ,” IEEE Transactions on Ultrasonics Ferroelectrics & Frequency Control 48(1):232-48, 2001. J. E. Chomas, P. Dayton, D. May, and K. Ferrara, ” Threshold of fragmentation for ultrasonic contrast agents ,” Journal of Biomedical Optics 6(2):141-50, 2001. P. A. Dayton, J. E. Chomas, A. F. Lum, J. S. Allen, J. R. Lindner, S. I. Simon, and K. W. Ferrara, ” Optical and acoustical dynamics of microbubble contrast agents inside neutrophils ,” Biophysical Journa l 80(3):1547-56, 2001. 2000J. E. Chomas, P. A. Dayton, D. May, J. Allen, A. Klibanov, and K. Ferrara, ” Optical observation of contrast agent destruction ,” Applied Physics Letters 77(7):1056-8, 2000. K. W. Ferrara, C. R. Merritt, P. N. Burns, F. S. Foster, R. F. Mattrey, and S. A. Wickline, ” Evaluation of tumor angiogenesis with US: imaging, Doppler, and contrast agents ,” Academic Radiology 7(10):824-39, 2000. D. Kruse and K. Ferrara, ” Color flow mapping ,” Ultrasound in Medicine and Biology 26(Suppl 1):S16-8, 2000. J. R. Lindner, P. A. Dayton, M. P. Coggins, K. Ley, J. Song, K. Ferrara, and S. Kaul, ” Noninvasive imaging of inflammation by ultrasound detection of phagocytosed microbubbles ,” Circulation 102(5):531-8, 2000. K. E. Morgan, J. S. Allen, P. A. Dayton, J. E. Chomas, A. L. Klibaov, and K. W. Ferrara, “ Experimental and theoretical evaluation of microbubble behavior: effect of transmitted phase and bubble size ,” IEEE Transactions on Ultrasonics Ferroelectrics & Frequency Control 47(6):1494-509, 2000. 1999P. Dayton, A. Klibanov, G. Brandenburger, and K. Ferrara, ” Acoustic radiation force in vivo: a mechanism to assist targeting of microbubbles ,” Ultrasound in Medicine and Biology 25(8):1195-201, 1999. P. A. Dayton, K. E. Morgan, A. L. Klibanov, G. H. Brandenburger, and K. W. Ferrara, ” Optical and acoustical observations of the effects of ultrasound on contrast agents ,” IEEE Transactions on Ultrasonics Ferroelectrics & Frequency Control 46(1):220-32, 1999. R. H. Silverman, D. E. Kruse, D. J. Coleman, and K. W. Ferrara, ” High-resolution ultrasonic imaging of blood flow in the anterior segment of the eye ,” Investigative Opthalmology & Visual Science 40(7):1373-81, 1999. 1998A. L. Klibanov, K. W. Ferrara, M. S. Hughes, J. H. Wible, Jr., J. K. Wojdyla, P. A. Dayton, K. E. Morgan, and G. H. Brandenburger, “ Direct video-microscopic observation of the dynamic effects of medical ultrasound on ultrasound contrast microspheres ,” Investigative Radiology 33(12):863-70, 1998. ( Microsoft Word , HTML ) D. E. Kruse, R. H. Silverman, R. J. Fornaris, D. J. Coleman, and K. W. Ferrara, ” A swept-scanning mode for estimation of blood velocity in the microvasculature ,” IEEE Transactions on Ultrasonics Ferroelectrics & Frequency Control 45(6):1437-40, 1998. K. E. Morgan, M. Averkiou, and K. Ferrara, ” The effect of the phase of transmission on contrast agent echoes ,” IEEE Transactions on Ultrasonics Ferroelectrics & Frequency Control 45(4):872-5, 1998. K. E. Morgan, P. A. Dayton, D. E. Kruse, A. L. Klibanov, G. H. Brandenburger, and K. W. Ferrara, “ Changes in the echoes from ultrasonic contrast agents with imaging parameters ,” IEEE Transactions on Ultrasonics Ferroelectrics & Frequency Control 45(6):1537-48, 1998. B. G. Zagar, R. J. Fornaris, and K. W. Ferrara, “ Ultrasonic mapping of the microvasculature: signal alignment ,” Ultrasound in Medicine and Biology 24(6):809-24, 1998. 1997P. A. Dayton, K. E. Morgan, A. L. Klibanov, G. Brandenburger, K. R. Nightingale, and K. W. Ferrara, ” A preliminary evaluation of the effects of primary and secondary radiation forces on acoustic contrast agents ,” IEEE Transactions on Ultrasonics Ferroelectrics & Frequency Control 44(6):1264-77, 1997. A. I. el-Fallah, M. B. Plantec, and K. W. Ferrara, ” Ultrasonic measurement of breast tissue motion and the implications for velocity estimation ,” Ultrasound in Medicine and Biology 23(7):1047-57, 1997. K. Ferrara and G. DeAngelis, ” Color flow mapping ,” Ultrasound in Medicine and Biology 23(3):321-45, 1997. pre-1997K. W. Ferrara, B. Zagar, J. Sokil-Melgar, and V. R. Algazi, ” High resolution 3D color flow mapping: applied to the assessment of breast vasculature ,” Ultrasound in Medicine and Biology 22(3):293-304, 1996. K. W. Ferrara, B. G. Zager, J. B. Sokil-Melgar, R. H. Silverman, and I. M. Aslanidis, ” Estimation of blood velocity with high frequency ultrasound ,” IEEE Transactions on Ultrasonics Ferroelectrics & Frequency Control 43(1):149-57, 1996. K. W. Ferrara, M. Ostromogilsky, S. Rosenberg, and J. Sokil-Melgar, ” Parameter mapping for the detection of disturbed blood flow ,” Ultrasound in Medicine and Biology 21(4):517-25, 1995. |